diff --git a/backend/alembic/versions/e0764f6d7c21_add_tag_ids_array_brin_indexes.py b/backend/alembic/versions/e0764f6d7c21_add_tag_ids_array_brin_indexes.py
new file mode 100644
index 0000000..178f053
--- /dev/null
+++ b/backend/alembic/versions/e0764f6d7c21_add_tag_ids_array_brin_indexes.py
@@ -0,0 +1,62 @@
+"""add_tag_ids_array_brin_indexes
+
+Revision ID: e0764f6d7c21
+Revises: g0h1i2j3k4l5
+Create Date: 2026-07-27 16:14:29.454432
+"""
+from typing import Sequence, Union
+from alembic import op
+import sqlalchemy as sa
+from sqlalchemy.dialects import postgresql
+
+revision: str = 'e0764f6d7c21'
+down_revision: Union[str, None] = 'g0h1i2j3k4l5'
+branch_labels: Union[str, Sequence[str], None] = None
+depends_on: Union[str, Sequence[str], None] = None
+
+
+def upgrade() -> None:
+    # ### commands auto generated by Alembic - please adjust! ###
+    op.drop_index(op.f('ix_audit_action'), table_name='audit_logs')
+    op.drop_index(op.f('ix_audit_actor'), table_name='audit_logs')
+    op.drop_table('audit_logs')
+    op.add_column('global_literature', sa.Column('tag_ids', postgresql.ARRAY(sa.Uuid()), nullable=True))
+    op.drop_index(op.f('ix_gl_authors_text_trgm'), table_name='global_literature', postgresql_ops={'(authors::text)': 'gin_trgm_ops'}, postgresql_using='gin')
+    op.create_index('ix_gl_is_negative_true', 'global_literature', ['is_negative_result'], unique=False, postgresql_where=sa.text('is_negative_result = TRUE'))
+    op.create_index('ix_gl_is_oa_true', 'global_literature', ['is_oa'], unique=False, postgresql_where=sa.text('is_oa = TRUE'))
+    op.create_index('ix_gl_is_preprint_true', 'global_literature', ['is_preprint'], unique=False, postgresql_where=sa.text('is_preprint = TRUE'))
+    op.create_index('ix_gl_pub_date_brin', 'global_literature', ['pub_date'], unique=False, postgresql_using='brin')
+    op.create_index('ix_gl_pub_date_covering', 'global_literature', ['pub_date', 'id'], unique=False, postgresql_include={'citation_status', 'is_oa', 'cited_by_count', 'is_preprint', 'pub_year', 'doi', 'journal_issn', 'is_negative_result', 'article_date', 'retracted', 'journal', 'language', 'pmc_id'})
+    op.create_index('ix_gl_pub_year_brin', 'global_literature', ['pub_year'], unique=False, postgresql_using='brin')
+    op.create_index('ix_gl_retracted_true', 'global_literature', ['retracted'], unique=False, postgresql_where=sa.text('retracted = TRUE'))
+    op.create_index('ix_gl_tag_ids_gin', 'global_literature', ['tag_ids'], unique=False, postgresql_using='gin')
+    # ### end Alembic commands ###
+
+
+def downgrade() -> None:
+    # ### commands auto generated by Alembic - please adjust! ###
+    op.drop_index('ix_gl_tag_ids_gin', table_name='global_literature', postgresql_using='gin')
+    op.drop_index('ix_gl_retracted_true', table_name='global_literature', postgresql_where=sa.text('retracted = TRUE'))
+    op.drop_index('ix_gl_pub_year_brin', table_name='global_literature', postgresql_using='brin')
+    op.drop_index('ix_gl_pub_date_covering', table_name='global_literature', postgresql_include={'citation_status', 'is_oa', 'cited_by_count', 'is_preprint', 'pub_year', 'doi', 'journal_issn', 'is_negative_result', 'article_date', 'retracted', 'journal', 'language', 'pmc_id'})
+    op.drop_index('ix_gl_pub_date_brin', table_name='global_literature', postgresql_using='brin')
+    op.drop_index('ix_gl_is_preprint_true', table_name='global_literature', postgresql_where=sa.text('is_preprint = TRUE'))
+    op.drop_index('ix_gl_is_oa_true', table_name='global_literature', postgresql_where=sa.text('is_oa = TRUE'))
+    op.drop_index('ix_gl_is_negative_true', table_name='global_literature', postgresql_where=sa.text('is_negative_result = TRUE'))
+    op.create_index(op.f('ix_gl_authors_text_trgm'), 'global_literature', [sa.literal_column('(authors::text)')], unique=False, postgresql_ops={'(authors::text)': 'gin_trgm_ops'}, postgresql_using='gin')
+    op.drop_column('global_literature', 'tag_ids')
+    op.create_table('audit_logs',
+    sa.Column('id', sa.UUID(), autoincrement=False, nullable=False),
+    sa.Column('actor_id', sa.UUID(), autoincrement=False, nullable=False),
+    sa.Column('tenant_id', sa.UUID(), autoincrement=False, nullable=True),
+    sa.Column('action', sa.VARCHAR(length=50), autoincrement=False, nullable=False),
+    sa.Column('target_type', sa.VARCHAR(length=50), autoincrement=False, nullable=True),
+    sa.Column('target_id', sa.VARCHAR(length=100), autoincrement=False, nullable=True),
+    sa.Column('detail', sa.TEXT(), autoincrement=False, nullable=True),
+    sa.Column('ip_address', sa.VARCHAR(length=45), autoincrement=False, nullable=True),
+    sa.Column('created_at', postgresql.TIMESTAMP(timezone=True), server_default=sa.text('now()'), autoincrement=False, nullable=False),
+    sa.PrimaryKeyConstraint('id', name=op.f('audit_logs_pkey'))
+    )
+    op.create_index(op.f('ix_audit_actor'), 'audit_logs', ['actor_id', 'created_at'], unique=False)
+    op.create_index(op.f('ix_audit_action'), 'audit_logs', ['action', 'created_at'], unique=False)
+    # ### end Alembic commands ###
diff --git a/backend/app/models/literature.py b/backend/app/models/literature.py
index 0621afa..0cfd9b6 100644
--- a/backend/app/models/literature.py
+++ b/backend/app/models/literature.py
@@ -3,7 +3,7 @@
 import uuid
 from datetime import date, datetime
 
-from sqlalchemy import Boolean, Date, DateTime, ForeignKey, Index, Integer, String, Text, Uuid, UniqueConstraint, func
+from sqlalchemy import Boolean, Date, DateTime, ForeignKey, Index, Integer, String, Text, Uuid, UniqueConstraint, func, text
 from sqlalchemy.dialects.postgresql import ARRAY, JSONB, TSVECTOR
 from sqlalchemy.orm import Mapped, mapped_column
 
@@ -78,11 +78,33 @@ class GlobalLiterature(Base):
     suppl_mesh_list: Mapped[dict] = mapped_column(JSONB, default=list)       # SupplMeshList [{descriptor, ui, type}]
     pharmacological_actions: Mapped[dict] = mapped_column(JSONB, default=list)  # PharmacologicalAction [{name, ui}]
 
+    tag_ids: Mapped[list | None] = mapped_column(ARRAY(Uuid))       # 标签 ID 数组 + GIN，免 JOIN global_literature_tags
+
     source: Mapped[str] = mapped_column(String(30), default="pubmed_ftp")
     created_at: Mapped[datetime] = mapped_column(DateTime(timezone=True), server_default=func.now())
     updated_at: Mapped[datetime] = mapped_column(DateTime(timezone=True), server_default=func.now(), onupdate=func.now())
 
     __table_args__ = (
+        # 时序数据 BRIN 代替 B-tree：pub_date/pub_year 物理相关性高，BRIN 体积小两个数量级
+        Index("ix_gl_pub_date_brin", "pub_date", postgresql_using="brin"),
+        Index("ix_gl_pub_year_brin", "pub_year", postgresql_using="brin"),
+
+        # Covering index：date 排序 + 高频引用列（index-only scan，排除大 TEXT/JSONB）
+        Index("ix_gl_pub_date_covering", "pub_date", "id",
+              postgresql_include={"journal_issn", "cited_by_count", "is_oa", "retracted",
+                                  "is_negative_result", "is_preprint", "journal", "pub_year",
+                                  "article_date", "doi", "pmc_id", "language", "citation_status"}),
+
+        # 高频筛选 partial index
+        Index("ix_gl_retracted_true", "retracted", postgresql_where=text("retracted = TRUE")),
+        Index("ix_gl_is_oa_true", "is_oa", postgresql_where=text("is_oa = TRUE")),
+        Index("ix_gl_is_negative_true", "is_negative_result", postgresql_where=text("is_negative_result = TRUE")),
+        Index("ix_gl_is_preprint_true", "is_preprint", postgresql_where=text("is_preprint = TRUE")),
+
+        # 反范式 tag_ids GIN 索引：标签筛选免 JOIN global_literature_tags
+        Index("ix_gl_tag_ids_gin", "tag_ids", postgresql_using="gin"),
+
+        # 保留旧 B-tree 兼容（迁移后旧索引下线，IR 移除时机：所有实例完成 migration）
         Index("ix_gl_pub_date", "pub_date"),
         Index("ix_gl_pub_year", "pub_year"),
         Index("ix_gl_journal_issn", "journal_issn"),